iOS Blepharoptosis Detection AI (MobileNetV2)
Binary classification of blepharoptosis vs normal eyelids from near-field facial photographs
▸ More attributes
Brief overview
This study developed an iOS-based deep learning system for automated blepharoptosis detection from eyelid photographs captured with an iPad Mini 5. The model used a fully retrained MobileNetV2 convolutional neural network trained on 1,276 eyelid images from 714 subjects at a single Japanese centre. Using 5-fold cross-validation, the system achieved 83.0% sensitivity, 82.5% specificity, 82.8% accuracy, and an AUC of 0.900 for distinguishing blepharoptosis from normal eyelids. Score-CAM heatmaps suggested the network focused on clinically relevant eyelid features. No external validation, open-source code, pretrained weights, or prospective clinical deployment were reported, and the authors noted the model was only evaluated on Asian eyelids.
5-fold cross-validation: AUC 0.90; accuracy 0.83; sensitivity 0.83; specificity 0.83.
5-fold cross-validation: AUC 0.90; accuracy 0.83; sensitivity 0.83; specificity 0.83.
| Study design | Diagnostic accuracy study |
|---|---|
| Center type | Single-center |
| Patients | 606 |
| Images / eyes | 1276 images |
| Split | 5-fold cross-validation (no fixed percentage split reported) |
| Reporting frameworks | None stated |
| Age range | Mean 71.5 |
|---|---|
| Sex (% female) | Not reported |
| Race / ethnicity reported | N |
| Subgroup performance | N |
- Concept
- Prototype
- Internal val.
- External val.
- Regulator
- Clinical
▸ Why this score?
The APPRAISE-AI tool grades AI/ML medical studies across 24 items in 6 subdomains, scored independently by two reviewers. The total reflects the methodological transparency of the publication — not the underlying clinical value of the model.
How to read this: high scores in clinical relevance and reporting with low scores in methodological conduct, robustness, or reproducibility is the dominant pattern in ophthalmic AI today.
Quality bands: Low <40 · Moderate 40–59 · High 60–79 · Very High 80+. Most published ophthalmic AI sits in the Low–Moderate band; studies that break into High typically combine multi-center datasets, prospective evaluation, and open-source release.
Bibliographic record ▸
| Model ID | oculoplastics_tabuchi_2022 |
|---|---|
| Full author list | Nagasato, D., Masumoto, H., Tanabe, M., Ishitobi, N., Ochi, H., Shimizu, Y., & Kiuchi, Y. |
| Journal | Graefes Arch Clin Exp Ophthalmol |
| DOI | 10.1007/s00417-021-05475-8 |
| Conditions | Blepharoptosis |
Model internals ▸
| Architecture family | CNN |
|---|---|
| Architecture detail | MobileNetV2 CNN |
Disclosures ▸
| Funding | NR |
|---|---|
| Conflicts of interest | No conflicts |
Status, version, reviewers ▸
| Card status | Published |
|---|---|
| Card version | v1.0.0 |
| First added | 2026-04-28 |
| Last reviewed | 2026-04-28 |
| Reviewers | attribution opt-in pending |
Card changelog ▸
- 2026-04-28 initial publication (v1.0.0+BD18)